Ivermectin (Stromectol) is an antiparasitic medication used to treat a variety of conditions, including river blindness and certain types of roundworm infections. However, it is using now “off-label” for the prevention or treatment of COVID-19. Previously, the drug was only available in the form of a cream. Ivermectin tablets are currently available online under the brand name Stromectol in doses of 3, 6, and 12 mg. Stromectol is available as a generic drug and can be significantly cheaper compared to the branded version.
Prices start at $52 for a pack of 10 tablets. You can reduce the price even further ordering from Canadian Pharmacy.
| Brand Names: US, CA | Stromectol |
| Active ingredients: | ivermectin |
| Pharmacologic Category: | Anthelmintic |
| Dosage Forms: | Tablet Stromectol 3 mg, 6 mg, 12 mg |
| Administration: | Oral |
| Cost: | from $2.48 per pill |
| Where to buy? | Visit Online Pharmacy |
Indications
Orally administered ivermectin tablets is indicated as a broad-spectrum anti-parasitic for the treatment of intestinal strongyloidiasis caused by Strongyloides stercoralis and onchocerciasis caused by Onchocerca volvulus.
Ivermectin (Stromectol) is indicated for the treatment of scabies, caused by Sarcoptes scabiei. The treatment of scabies is only indicated if the diagnosis has been established clinically and/or by parasitological examination.
Ivermectin therapy is used internationally for the treatment of various tropical diseases, including filariasis, cutaneous larva migrans, and Loa loa infection, amongst others. The National Institutes of Health’s (NIH) COVID-19 Treatment Guidelines Panel has also determined that there are currently insufficient data to recommend ivermectin for treatment of COVID-19.
Mechanism of action
Avermectins, including ivermectin, are broad-spectrum antiparasitic agents. They bind selectively and with high affinity to glutamate-gated chloride ion channels present in invertebrate nerve and muscle cells. This binding leads to an increase in the permeability of the cell membrane to chloride ions with hyperpolarization of the nerve or muscle cell, resulting in paralysis and death of the parasite. This class of compounds may also bind with other ligand-gated chloride channels, such as those gated by the neurotransmitter gamma-aminobutyric acid (GABA). The avermectins’ selectivity is due to the fact that some mammals do not have glutamate-gated chloride channels and that the avermectins have a low affinity for mammalian ligand-gated chloride channels. Ivermectin does not cross the blood-brain barrier in humans.
Dosing
The dose of this medicine will be different for different patients. Follow your doctor’s orders or the directions on the label. The following information includes only the average doses of this medicine.
For oral dosage form (tablets):
For river blindness:
- Adults and children weighing 15 kilograms (kg) or more—Dose is based on body weight and must be determined by your doctor. The dose is usually 150 micrograms (mcg) per kilogram (kg) of body weight taken as a single dose. The treatment may be repeated every 3 to 12 months. Each tablet contains 3 milligrams (mg) of ivermectin.
- Weighing 85 kg or more—150 mcg/kg of body weight taken as a single dose.
- Weighing 65 to 84 kg—4 tablets taken as a single dose.
- Weighing 45 to 64 kg—3 tablets taken as a single dose.
- Weighing 26 to 44 kg—2 tablets taken as a single dose.
- Weighing 15 to 25 kg—1 tablet taken as a single dose.
- Children weighing less than 15 kg—Use and dose must be determined by your doctor.
For threadworms:
- Adults and children weighing 15 kilograms (kg) or more—Dose is based on body weight and must be determined by your doctor. The dose is usually 200 micrograms (mcg) per kilogram (kg) of body weight taken as a single dose. Each tablet contains 3 milligrams (mg) of ivermectin.
- Weighing 80 kg or more—200 mcg/kg of body weight taken as a single dose.
- Weighing 66 to 79 kg—5 tablets taken as a single dose.
- Weighing 51 to 65 kg—4 tablets taken as a single dose.
- Weighing 36 to 50 kg—3 tablets taken as a single dose.
- Weighing 25 to 35 kg—2 tablets taken as a single dose.
- Weighing 15 to 24 kg—1 tablet taken as a single dose.
- Children weighing less than 15 kg—Use and dose must be determined by your doctor.
Can I Buy Ivermectin over the counter online?
Many people wonder how to get ivermectin and if ivermectin over the counter is available. All forms of ivermectin for humans, including ivermectin tablets and ivermectin cream, are prescription medications in the United States. As a result, one cannot just buy ivermectin online or get ivermectin OTC as pharmacies will not dispense it without first getting an ivermectin prescription.
The first step to getting a prescription is a visit to the doctor. If you do not have the opportunity to visit a doctor, you can seek help from online pharmacies that use the simplified legislation of neighboring countries and offer the opportunity to order Ivermectin online from Canada. This does not require a prescription and the price will be cheaper by an average of 40-60%.
How much does Ivermectin cost in Canada?
The cost for generic Ivermectin oral tablet 3 mg is around $52 for a supply of 10 tablets, depending on the pharmacy you visit. Canadian Online Pharmacies serves as a more affordable alternative for getting the medicines you need. As part of our commitment to providing customers with the best value on drugs, we sell Ivermectin tablets 20% below traditional retail costs. STROMECTOL (Ivermectin) comes as a 3 mg, 6 mg and 12 mg tablets in a pack of 10, 30, 60, 90 ot 180 tablets. Our pharmacy offers Ivermectin 3mg tablet blister pack containing 10 tablets for $41.95.
The price for a pack of 10 Ivermectin 6mg tablets is $47.80
The cost of Ivermectin 12mg per blister containing 10 tablets is $67.10.
You can also get free shipping on orders over $200.
How to take Ivermectin?
Ivermectin comes in the form of tablets. Usually it’s taken as a single dose and it should be taken in an empty stomach with water. Follow the direction mentioned on your prescription also before taking Ivermectin consult with your doctor for knowing the perfect dosage timing. Take Ivermectin as directed by your doctor or it may lead to some serious side effects.
If you are taking Ivermectin for the treatment of Strongyloidiasis you need to go for a stool exam at least 3 times for the first 3 months after the treatment for knowing if your infection has cleared or not.
Drug interactions
Drug interactions can cause side effects and change how medications work. There is a risk of other drugs interacting with ivermectin. These include over-the-counter (OTC) drugs, prescription drugs, herbal remedies, and vitamins. Some products/drugs that may interact with ivermectin include the following:
- Anti-anxiety medicines, like lorazepam (Ativan and Lorazepam Intensol) and clonazepam (Klonopin)
- Sedatives, like phenobarbital and butalbital
- Antiepileptic drugs, like valproic acid (Depakene and Depakote)
Tell your doctor which medicines you are currently taking. You also need to inform them about any medication you stop or start taking during treatment with ivermectin.
Side effects of Ivermectin
All drugs may cause side effects. However, many people have no side effects or only have minor side effects.
Common side effects of this drug are:
- Dizziness, tiredness, stomach upset, loss of appetite, shakiness, sleepiness, skin rash or itching is experienced with oral preparations.
- Burning sensation and skin irritation are few side effects associated with topical formulations of Ivermectin.
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